On Biostatistics and Clinical Trials: SAD and MAD: Single Ascending Dose and Multiple Ascending Dose first-in-human studies
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers | BMC Pulmonary
The phases of preclinical and clinical trials
Study design: (A) single ascending dose; (B) multiple ascending dose. | Download Scientific Diagram
Statistical considerations in exploratory studies
Safety, tolerability, and pharmacokinetics of TPN171H - DDDT | DDDT
STATISTICAL ANALYSIS PLAN Protocol PQ-010-001 PHASE 1B, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, DOSE ESCALATION STUDY TO
Pharmacokinetics of ASP4345 from Single Ascending-Dose and Multiple Ascending-Dose Phase I Studies | SpringerLink
Traditional Process First in Human Single Ascending Dose Multiple Ascending Dose U.S.A. Japan Phase II Phase III NDA in Japan Phase II Phase III NDA in. - ppt download
Pharmacokinetics of ASP4345 from Single Ascending-Dose and Multiple Ascending-Dose Phase I Studies | SpringerLink
Single and multiple ascending dose GS-9256 and GS-9451 clinical trial... | Download Scientific Diagram
JCI - Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus
Types of Study in Early Clinical Development - EUPATI Toolbox
Two Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Studies To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody, MHAA4549A, in Healthy Volunteers | Antimicrobial ...
Single Ascending Dose & Multiple Ascending Dose
Schematic of the ECG timepoints and meals in the single-ascending dose... | Download Scientific Diagram
Study design with overlapping SAD-MAD cohorts, where treatment periods... | Download Scientific Diagram
Single and Multiple Ascending-dose Studies of Oral Delafloxacin: Effects of Food, Sex, and Age - ScienceDirect
Frontiers | Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial
Phase I Trial of Anti–Vascular Endothelial Growth Factor/Anti-angiopoietin 2 Bispecific Antibody RG7716 for Neovascular Age-Related Macular Degeneration - ScienceDirect
Study design. The study included single and multiple ascending... | Download Scientific Diagram
ONCE-DAILY REGIMENS OF THE HCV NS3/4A-PROTEASE INHIBITOR TMC435350 ARE PREDICTED TO PROVIDE THERAPEUTIC EXPOSURE IN PLASMA AND LIVER
Single Ascending Dose & Multiple Ascending Dose
